The AI Family Tree: Predicting Generations with Genetics and Machine Learning

Stuart Kerr
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AI tools are now reading our genes to shape the future—literally. From embryo screening to inherited risk scores, algorithms are being trained to decode tomorrow’s children before they’re even born.

By Stuart Kerr, Technology Correspondent
Published: 17 July 2025
Last Updated: 17 July 2025
Contact: liveaiwire@gmail.com | Twitter: @LiveAIWire


Algorithmic Ancestry: A New Branch in Genetics

In labs across the world, artificial intelligence is learning to predict everything from eye colour to Alzheimer’s risk—based not on science fiction, but on real-world genomic data. Machine learning models are now being integrated into fertility clinics, where startups like Orchid Health offer polygenic risk scores to prospective parents choosing embryos.

According to a Washington Post investigation, this technology is already in clinical use, scoring embryos on potential future health conditions such as heart disease, mental illness, and diabetes. It’s a shift that promises preventative care—but also raises deep ethical questions about eugenics, choice, and inequality.

The Science of Possibility, Not Certainty

AI’s role in genomics is not to predict exact outcomes, but to offer statistical guidance. As AI & Ethics Journal notes, these polygenic tools are probabilistic. They operate in a grey zone—between prediction and influence. Yet in a culture obsessed with optimisation, even probability can drive powerful decisions.

Critics argue that assigning value to embryos based on machine learning models runs the risk of commodifying life itself. At what point does a risk score become a label? And what happens when parents begin to select not just for health, but for traits such as intelligence or athletic potential?

These concerns echo a broader theme explored in LiveAIWire’s report on AI in mental health, where algorithmic judgement on human complexity often oversimplifies real-world nuance.

Ethics Under the Microscope

A detailed PDF report by the Journal of Community Genetics highlights the moral complexity of AI-guided genetics. Concerns include bias in datasets, lack of transparency in scoring algorithms, and the risk of reinforcing racial or socioeconomic disparities.

These fears are not abstract. The CDC’s public health review on AI fairness warned that underrepresented groups are often excluded from training data, leading to skewed outcomes that disproportionately affect marginalised populations. In reproductive medicine, where decisions have lifelong consequences, even a small bias can produce generational effects.

At the same time, AI is revolutionising genomics research, compressing years of data modelling into seconds. The NHGRI Machine Learning Workshop documented how AI is being used to interpret variants of unknown significance in patient genomes—an advance that could democratise genetic insight, provided the right safeguards are in place.

Tomorrow’s Child, Today’s Code

The implications extend far beyond the clinic. In future school admissions, insurance coverage, and employment, could polygenic profiles become the new biometric? If so, society will need strong regulations to prevent genetic data from becoming destiny.

Already, discussions about AI’s ability to simulate human traits—like those in LiveAIWire’s emotional intelligence feature—point to a troubling paradox. The more we quantify human potential, the less space we leave for uncertainty, individuality, and surprise.

As parents, policymakers, and technologists grapple with this new era of predictive biology, one thing is clear: the technology is moving faster than the ethics.

Navigating a Genomic Future

AI’s potential in genomics is vast—from early detection of genetic disorders to tailoring personalised treatments. But when these tools are used to guide the very act of reproduction, the stakes rise dramatically.

In an age where your child’s future may be scored before birth, the challenge lies not in what AI can do—but in deciding what it should do. Predictive genomics, like all technologies, reflects the values of those who wield it.

As explored in LiveAIWire’s coverage of AI in wellness, choice remains a central issue. Empowerment becomes coercion the moment AI advice feels compulsory. In the world of polygenic embryo screening, informed consent must mean more than a signature—it must mean understanding.




Alt Text for Featured Image: A digital DNA strand morphs into a human silhouette, surrounded by floating AI-generated data panels in a clinical lab setting.

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